Spironolactone didn't improve outcomes post-heart attack but may reduce new heart failures, study shows.

The CLEAR SYNERGY trial found that spironolactone did not improve outcomes for patients after a heart attack who underwent a specific procedure. While it didn't reduce the risk of cardiovascular death or heart failure, it showed a potential benefit in reducing new or worsening heart failure when patients stayed on the medication. However, it caused more patients to stop taking the drug due to side effects like elevated potassium levels and gynecomastia. Further research is needed to clarify its role in heart health.

November 17, 2024
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