Cabaletta Bio's CABA-201 shows promise in treating autoimmune diseases with no serious side effects.

Cabaletta Bio presented positive data on its therapy CABA-201 at the ACR Convergence 2024, showing good safety and efficacy in patients with autoimmune diseases like lupus and myositis. The therapy, a 4-1BB-containing CD19-CAR T cell treatment, demonstrated no serious side effects in most patients and led to B cell depletion, potentially allowing for a drug-free remission. The company is testing CABA-201 in five clinical trials and plans to meet with the FDA in 2025 to discuss future trial designs.

November 18, 2024
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