Intellia Therapeutics' CRISPR therapy shows promising results in treating ATTR amyloidosis.

Intellia Therapeutics reported positive results from a Phase 1 trial of nexiguran ziclumeran, a CRISPR-based gene therapy for ATTR amyloidosis. The treatment showed rapid and lasting reductions in disease markers and improvements in patient conditions after a single dose. The therapy was found to be safe and well-tolerated, with benefits observed in both heart and nerve-related symptoms of the disease.

November 16, 2024
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