FDA approves Revuforj for treating specific acute leukemia cases in patients of all ages.

The FDA has approved Revuforj (revumenib), the first menin inhibitor for treating relapsed or refractory acute leukemia in patients with a KMT2A gene translocation, including adults and children aged one year and older. Based on the AUGMENT-101 trial, Revuforj showed a 21.2% complete remission rate with a median response duration of 6.4 months. Common side effects include hemorrhage, nausea, and increased phosphate levels.

November 15, 2024
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