Zymeworks begins Phase 1 trial for ZW191, a drug targeting advanced solid tumors expressing FR-α.

Zymeworks has initiated a Phase 1 clinical trial for its drug ZW191, which aims to treat advanced solid tumors that express the folate receptor-α (FR-α), such as ovarian and lung cancers. The trial, involving 145 adult patients, will assess the drug's safety, tolerability, and potential effectiveness. ZW191 is designed as an antibody-drug conjugate that targets FR-α to deliver a cytotoxic agent directly to cancer cells, marking a significant step for Zymeworks.

November 05, 2024
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