Novartis's Fabhalta® showed significant improvement in C3 glomerulopathy patients, with plans for FDA approval by year-end.

Novartis announced promising results from the Phase III APPEAR-C3G study, indicating that its oral drug Fabhalta® (iptacopan) significantly reduced proteinuria and improved kidney function in patients with C3 glomerulopathy (C3G) over one year. This ultra-rare kidney disease currently has no approved treatments. Novartis plans to seek FDA approval for Fabhalta in C3G by year-end, following submissions in other regions.

October 26, 2024
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