Nurix Therapeutics reports 77.8% response rate in Phase 1a/1b trial of NX-5948, a BTK degrader for relapsed/refractory Waldenstrom'

Nurix Therapeutics has reported promising outcomes from its Phase 1a/1b trial of NX-5948, a BTK degrader for relapsed/refractory Waldenstrom's macroglobulinemia. The trial showed a 77.8% objective response rate among evaluable patients, with some responses lasting over a year. These findings, shared at the IWWM-12 workshop, support further development of NX-5948, particularly for patients previously treated with BTK inhibitors and those with central nervous system involvement.

October 19, 2024
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