Wave Life Sciences announces successful Phase 1b/2a study showing efficacy of WVE-006 for alpha-1 antitrypsin deficiency, causing stock surge.

Wave Life Sciences Ltd. announced successful proof-of-mechanism data from its Phase 1b/2a RestorAATion-2 study of WVE-006, the first-ever therapeutic RNA editing treatment in humans for alpha-1 antitrypsin deficiency (AATD). The treatment demonstrated significant efficacy in raising protective protein levels. Following the announcement, the company’s stock surged by over 75%. Wave plans to present more data in 2025 and hosts a virtual Research Day on October 30, 2024.

October 16, 2024
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