Researchers develop drug RI-AG03 targeting Alzheimer's-linked tau proteins, extending fruit fly lifespan and reducing neuron degeneration in human cells.

Researchers have developed a promising drug, RI-AG03, which targets specific 'hotspots' on tau proteins linked to Alzheimer's disease. In tests on fruit flies, RI-AG03 extended their lifespan by 35% and reduced neuron degeneration in human cells. This peptide inhibitor's dual-targeting mechanism may lead to more effective treatments for neurodegenerative diseases. Next steps involve testing on mice and moving to clinical trials.

October 07, 2024
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