Study finds age-related changes in male fibroblasts contribute to aggressive, treatment-resistant melanoma.

A study from Johns Hopkins Kimmel Cancer Center reveals that age-related changes in fibroblasts contribute to aggressive, treatment-resistant melanoma in men, who are at higher risk than women. Male fibroblasts age faster and produce more reactive oxygen species, increasing cancer severity. The research highlights the need to understand sex differences and cellular changes for developing tailored therapies targeting melanoma.

September 06, 2024
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