FDA grants tentative approval to Liquidia's YUTREPIA, pending expiration of Tyvaso DPI exclusivity.

Liquidia Corp's stock dropped nearly 22% after the FDA granted a tentative approval for its inhalation powder, YUTREPIA, to treat adults with pulmonary arterial hypertension (PAH) and pulmonary hypertension (PH-ILD). The tentative approval indicates that YUTREPIA has met all regulatory standards but must await the expiration of regulatory exclusivity of a competing product, United Therapeutics' Tyvaso DPI, before final approval can be granted. The final approval for YUTREPIA for PAH and PH-ILD is expected after the expiration of 3-year regulatory exclusivity for Tyvaso DPI on May 23, 2025. Liquidia's CEO, Roger Jeffs, expressed disappointment with the FDA's decision to grant regulatory exclusivity to United Therapeutics for Tyvaso DPI and plans to take quick action to challenge the decision and defend the ability for patients to have access to YUTREPIA with the least delay possible.

August 19, 2024
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