Yale researchers discover spontaneous cellular activity drives early brain wiring during development, guided by Hebb's rule.

Yale researchers find spontaneous cellular activity plays a key role in early brain wiring during development. Focusing on mouse retinal ganglion cells, they discovered when cells fire together, "wiring together" occurs, guided by Hebb's rule. This study provides insight into brain development, potentially explaining the basis of learning, and will continue to explore axon branching patterns in relation to connected neurons.

August 15, 2024
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