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128,294 UK women study by Cardiff University et al. finds perimenopause raises risk of bipolar disorder by 112% and major depressive disorder onset by 30%.
Researchers from Cardiff University, Bipolar UK, and the UK Biobank have found that women in perimenopause are more likely to develop bipolar disorder, with a 112% increase in risk, and a 30% increase in the onset of major depressive disorder.
The study of 128,294 UK women, published in Nature Mental Health, is the first to demonstrate a measurable impact of menopausal transition on women's mental health.
The findings may help predict individual risk of mental health issues during this time, potentially saving lives, and could provide additional support for women experiencing these changes.
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128.294 mujeres del Reino Unido estudian en la Universidad de Cardiff et al. La perimenopausia aumenta el riesgo de trastorno bipolar en un 112% y el inicio de un trastorno depresivo mayor en un 30%.