Study suggests reversing menopause-related body fat changes through blocking receptor Cxcr4 and low-dose estrogen therapy.

A Nature Communications study suggests potential therapies for reversing unhealthy body fat changes during menopause, linked to cardiovascular and metabolic diseases. Blocking receptor Cxcr4 in mice reduced white fat development, and combining it with low-dose estrogen therapy could change body fat distribution in menopausal women, preventing diseases. This research could help understand healthy and unhealthy fat tissue development and reduce white fat in postmenopausal women.

August 14, 2024
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