Study in eLIFE shows JAK inhibitors, like tofacitinib, effectively treat autoimmune conditions in people with Down syndrome.

A study in eLIFE reveals that JAK inhibitors, like tofacitinib, can effectively treat autoimmune conditions in people with Down syndrome. The trial, conducted by the Linda Crnic Institute for Down Syndrome, demonstrated improvements in skin pathology, notably for alopecia areata, and potential benefits for other autoimmune conditions. However, further analysis is needed to define the safety profile of JAK inhibitors for this population.

August 13, 2024
3 Articles

Further Reading