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Researchers at Johns Hopkins developed four regimens for treating multidrug-resistant TB meningitis using FDA-approved antibiotics.
Researchers at Johns Hopkins Children's Center have developed four new regimens for treating multidrug-resistant (MDR) tuberculous (TB) meningitis, primarily using FDA-approved and clinical trial antibiotics.
The regimens, which could be readily evaluated in new clinical studies or used on a case-by-case basis, show promise in treating MDR-TB meningitis, which is a challenging form of the disease.
The study utilized PET and CT imaging on patients, rabbits, and mice to demonstrate how different antibiotics penetrate the brain and other body areas.
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Investigadores de Johns Hopkins desarrollaron cuatro regímenes para tratar la meningitis multirresistente por tuberculosis utilizando antibióticos aprobados por la FDA.