Researchers found cocaine triggers NPAS4 protein to promote drug-taking behavior, potentially aiding in new addiction therapies.

Researchers at the Medical University of South Carolina discovered that cocaine triggers a protein, NPAS4, in the brain to hijack normal brain circuitry and promote further drug-taking behavior. NPAS4 is involved in the formation and maintenance of drug-context associations, which are critical factors in relapse vulnerability. This breakthrough could lead to new therapeutic targets aimed at reducing the risk of relapse, providing a significant advancement in the battle against cocaine addiction.

August 09, 2024
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