Researchers at UC Davis developed CaST, a non-invasive tool to track neurons and biomolecules activated by psychedelic drugs, which may help treat brain disorders.

Researchers at UC Davis created a rapid, non-invasive tool, Ca2+-activated Split-TurboID (CaST), to track neurons and biomolecules activated by psychedelic drugs in the brain. This protein-based tool allows scientists to study the cellular mechanisms of psychedelics like LSD, DMT, and psilocybin, which may help treat brain disorders such as depression, PTSD, and substance use disorder. CaST works by tagging cells with biotin, detectable using commercial tools, and enables brain-wide cellular labeling.

August 05, 2024
3 Articles