Cornell researchers identified a switch regulating inflammation caused by immune responses, involving kinase ITK and calcium.

Cornell researchers discovered a switch regulating inflammation caused by immune responses. By identifying the roles played by kinase ITK, an enzyme, and calcium in controlling this switch, they found that it determines whether T cells develop as inflammatory TH17 cells or anti-inflammatory Treg cells. This finding could potentially help clinicians control inflammation-related conditions like autoimmune, cardiovascular, and neurodegenerative diseases.

July 24, 2024
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