UNC School of Medicine researchers found a link between migraine pain and the brain's lymphatic drainage, involving protein CGRP.

Researchers at the UNC School of Medicine discovered a connection between the brain's lymphatic drainage and migraine pain. A protein called calcitonin gene-related peptide (CGRP) impacts the lymphatic vascular system, preventing cerebrospinal fluid from draining through the meningeal lymphatic vessels, and leading to pain during migraine attacks. This study highlights the importance of the brain's lymphatic system in migraine pain pathophysiology.

July 11, 2024
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