2021 Mass General Brigham study finds maternal Alzheimer's history increases risk of inheriting Alzheimer's compared to paternal history.

A recent study by Mass General Brigham suggests that having a mother with Alzheimer's disease increases the risk of inheriting the condition compared to a paternal history. The research analyzed 4,400 adults aged 65-85, with amyloid detected in their brain-imaging scans, and found a correlation between maternal history of dementia and preclinical Alzheimer's disease, while paternal history had less impact.