Researchers at Helmholtz Institute developed IMPRINT, a novel method to enhance DNA transformation in bacteria using methyltransferases.

Researchers at Helmholtz Institute for RNA-based Infection Research developed IMPRINT, a novel method to enhance DNA transformation in bacteria. It uses a cell-free transcription-translation system to express methyltransferases, which then methylate DNA before delivery. This method improves transformation in various bacteria, opening possibilities for new antibiotics, cell-based therapies, and research.