Researchers at Weill Cornell Medicine-Qatar used CRISPR to discover UHRF1's role in fat cell formation and fibrosis regulation, linking it to obesity and type 2 diabetes.
Researchers at Weill Cornell Medicine-Qatar have discovered the role of a protein called UHRF1 in regulating new fat cell formation (adipogenesis) using CRISPR gene editing technology. UHRF1 also suppresses fibrosis, the hardening or scarring of bodily tissues, which is linked to inflammatory diseases and insulin resistance. Their findings shed light on potential causes of obesity and its complications, such as type 2 diabetes.
June 24, 2024
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