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Researchers at Max Delbrück Center developed high-resolution spatial transcriptomics platform Open-ST, creating 3D molecular maps from patient tissue samples for drug target discovery.
Researchers at the Max Delbrück Center have developed an open-source platform, Open-ST, that creates 3D molecular maps from patient tissue samples with subcellular precision.
This high-resolution spatial transcriptomics platform allows scientists to reconstruct gene expression in cells within a tissue, potentially helping researchers discover drug targets and new therapies.
The study was published in the journal "Cell."
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Investigadores del Centro Max Delbrück desarrollaron la plataforma de transcriptómica espacial de alta resolución Open-ST, creando mapas moleculares en 3D a partir de muestras de tejido de pacientes para el descubrimiento de objetivos farmacológicos.