2nd-placed FC Cincinnati, without key defenders, faces 8th-placed Philadelphia Union in a midweek clash.

2nd-placed FC Cincinnati faces Philadelphia Union in a midweek clash, with key defenders Matt Miazga and Miles Robinson missing for Cincinnati due to injury and international duty. Cincinnati, on a 4-2 victory in San Jose, is determined to maintain their winning streak against the 8th-placed Philadelphia Union, who have points in four of their last five games. Both teams will meet again on Oct 19th.