Study in Nature shows obesity increases macrophages and PD-1 protein in tumors, potentially improving immunotherapy treatments.

A study published in Nature reveals that obesity increases the number of macrophages, immune system cells, in cancer tumors and their production of a protein called PD-1. This protein can help tumors grow, but when PD-1 is blocked through immunotherapy, it enhances the immune system's ability to fight cancer. This insight could help improve immunotherapy treatments by better understanding the biological processes involved.