University of Cambridge researchers develop mini-guts from Crohn's disease patient cells to better understand the condition and personalize treatments.
Researchers at the University of Cambridge have developed "mini-guts" from human cells donated by patients with Crohn's disease, a form of inflammatory bowel disease (IBD), to better understand the condition and potentially develop more personalised treatments. The mini-guts, or organoids, are grown from cells donated by affected individuals and can help researchers study the disease, test different drugs, and find the most effective treatment for individual patients. The study found that switches which modify DNA in gut cells play an important role in the disease and how it presents in patients, potentially opening up the possibility of tailoring treatments to individual patients.
June 10, 2024
41 Articles