Johns Hopkins Medicine scientists discovered how perampanel, a common epilepsy drug, controls seizures by super-chilling AMPA receptor brain cell molecules.
Scientists at Johns Hopkins Medicine discovered how a common epilepsy drug works to control seizures by super-chilling brain cell molecules. The research reveals the connections between the drug perampanel and the activity of AMPA receptors, a brain cell surface molecule. This finding may lead to designing new drugs targeting AMPA receptors to treat neurological conditions like Alzheimer's disease, schizophrenia, learning disabilities, brain cancer, and chronic pain.
June 10, 2024
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