Study finds bisphosphonates combined with azoles can improve dermatophyte fungal infection treatment, repurposing osteoporosis drugs.

A new study suggests that combining common bone loss drugs, bisphosphonates, with azoles can improve the efficacy of treating fungal infections caused by dermatophytes, which are resistant to azoles. Lab tests showed the combination worked against dermatophyte species and prevented resistance. This approach could repurpose bisphosphonates, usually used for osteoporosis, with azole antifungals, offering a potential solution to challenging fungal infections.

June 05, 2024
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