Ochsner Health researchers led by Dr. Hernan Bazan developed a non-opioid, non-addictive pain treatment, SRP-001, through a study published in Scientific Reports.
Ochsner Health researchers led by Dr. Hernan Bazan have developed a potentially groundbreaking non-opioid pain treatment, SRP-001, through a study published in Scientific Reports. SRP-001 triggers N-arachidonoylphenolamine (AM404) formation in the midbrain's periaqueductal grey (PAG) region, a potent activator of TRPV1 that plays a crucial role in the brain's response to pain. The medication is non-addictive, non-toxic, and offers a safer alternative to existing pain medications, with phase 1 trial results demonstrating safety, tolerability, and favorable pharmacokinetics.
May 16, 2024
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