2024 study finds centromere consists of two subdomains, impacting chromosome segregation errors in cell division.

Researchers from the Hubrecht Institute's Kops group and University of Edinburgh discovered that the centromere, crucial for proper chromosome segregation during cell division, consists of two subdomains. This finding has significant implications for understanding chromosome segregation errors leading to cell death or cancer development. The discovery was published in Cell on May 13, 2024.