47-year-old man develops irreversible brain damage from fentanyl inhalation, leading to toxic leukoencephalopathy.

New research shows inhaling the synthetic opioid fentanyl, approved for pain relief and anaesthetic by the US FDA, can cause irreversible brain damage. A 47-year-old man, found unresponsive in his hotel room after snorting fentanyl, was diagnosed with toxic leukoencephalopathy by fentanyl inhalation. This condition causes inflammation and damage to the brain's white matter, leading to potentially irreversible neurological and behavioral changes. This is the first documented case of brain damage associated with fentanyl inhalation.

April 29, 2024
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