10% of end-stage renal failure patients with chronic kidney disease of unknown origin had undiagnosed inherited kidney disease variants, emphasizing the need for genetic analysis.

Researchers at Tokyo Medical and Dental University analyzed genetic data from 1,164 end-stage renal failure patients with chronic kidney disease of unknown origin. Over 10% were found to have disease-causing variants of inherited kidney diseases, which often went undiagnosed clinically. These findings highlight the importance of genetic analysis in identifying hidden causes of chronic kidney disease.

April 03, 2024
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