University of Virginia researchers found a gene, Uty, linked to increased heart failure prevalence in men due to Y chromosome loss.

University of Virginia researchers discovered a gene, Uty, on the Y chromosome that contributes to increased heart failure prevalence in men. Y chromosome loss can lead to heart muscle scarring and heart failure, with Uty affecting immune cells and causing scarring. The study suggests potential treatments or prevention strategies for heart failure and fibrotic diseases in men with Y chromosome loss.