Oprah Winfrey reveals struggles with weight loss and addresses obesity myths in "An Oprah Special: Shame, Blame, and the Weight Loss Revolution."

Oprah Winfrey has opened up about her struggle with weight loss after two decades of her body being under scrutiny. In a recent TV special, she said, "For 25 years, making fun of my weight was national sport." The TV special, titled "An Oprah Special: Shame, Blame, and the Weight Loss Revolution," features Winfrey addressing myths surrounding obesity and the growing trend of weight management medication.