Johns Hopkins study links skin stiffening in aging to higher metastatic skin cancer rates via increased ICAM1 protein release.
The Johns Hopkins Kimmel Cancer Center study reveals that skin stiffening in aging individuals may contribute to higher rates of metastatic skin cancer. Increased skin stiffness leads to higher ICAM1 protein release, which stimulates tumor blood vessel growth, enabling cancer cell escape and spread. Researchers are studying ICAM1 to develop targeted drugs for treating older people with melanoma and other age-related cancers.
March 12, 2024
3 Articles