Actresses Christina Applegate and Jamie-Lynn Sigler discussed their MS diagnoses in a joint interview and podcast titled "MeSsy".

Actresses Christina Applegate and Jamie-Lynn Sigler have publicly discussed their shared battle with multiple sclerosis (MS) in a joint interview on Good Morning America. Applegate, diagnosed in 2021, and Sigler, diagnosed over 20 years ago, share their experiences in a new podcast titled "MeSsy". MS is an autoimmune disease that affects nerve function and is more common in women than men, with symptoms typically starting between ages 20 and 40.

March 11, 2024
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