IMBA's Burga Lab discovered a novel gene regulation process linked to selfish gene silencing in nematodes, potentially the first step in the evolution of imprinting.

The Burga Lab at IMBA discovered a novel gene regulation process linked to selfish gene silencing that could be the first step in the evolution of imprinting, a mechanism where genes are expressed or silenced based on maternal or paternal inheritance. Their discovery, published in Nature, suggests how and why imprinting first evolved, and it involves the first identified parent-of-origin effect in nematodes.

March 06, 2024
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