2024 CROI study finds semaglutide effective and safe for HIV patients with MASLD, reducing liver fat by 31%.

A study presented at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) revealed that semaglutide, the active ingredient in Novo Nordisk's Wegovy and Ozempic, is a safe and effective therapy for metabolic dysfunction-associated steatotic liver disease (MASLD) in individuals with HIV. The Phase 2b pilot study enrolled 49 participants with HIV and MASLD, who experienced an average 31% reduction in liver fat and a 29% complete resolution of MASLD, potentially aiding healthcare decisions in consultation with providers.

March 05, 2024
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