Researchers at Virginia Commonwealth University develop a urine-based, nanopore sensing test for early ovarian cancer detection using thousands of peptide markers.

A new urine-based test for ovarian cancer could help detect the disease early. Researchers at Virginia Commonwealth University have found that thousands of small molecules, called peptides, are present in the urine of individuals with ovarian cancer. However, existing detection methods are not straightforward or cost-effective. To address this issue, the team turned to nanopore sensing, which has the potential to simultaneously detect multiple peptides. This technique involves passing molecules through a tiny pore and measuring changes in electrical current or other properties as they move through.

February 10, 2024
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